The term dysgranular insular cortex (Roberts) refers to a cytoarchitecturally defined area of the insula. It is distinguished from neighboring agranular insular cortex (Roberts) by the presence of granule cells and from granular insula, on the opposite side, by the presence of a single, interrupted layer of lesser numbers of granule cells instead of two distinct layers. The density of granule cells follows a declining gradient from the border with granular insula to the border with agranular insular cortex (Roberts). In primates the dysgranular cortex forms a wide band that crosses the central insula obliquely between its caudoventral and rostrodorsal extremes ( Roberts-1963; Roberts-1970 ). In the human it is subdivided into three parts caudorostrally: insular dysgranular area 1, insular dysgranular area 2, and insular dysgranular area 3 ( Zilles-2012). Its location in the macaque is similar to that in the human, but it is not subdivided ( Roberts-1963; Paxinos-2009a ). In the rat ( Swanson-1998 ) and the mouse ( Paxinos-2001 ) it is located on the smooth ventrolateral surface of the rostral third of the cerebral cortex, dorsal to the agranular insular cortex (Roberts) and ventral to the secondary somatosensory cortex (rostrally) and the granular insula (caudally).