perifornical area - BrainInfo

perifornical area (PFX)

The term perifornical area (PFX) refers to a structurally and functionally defined group of neurons variously illustrated as surrounding, dorsal to, or ventral to the postcommissural fornix (pofx) at the level of the ventromedial nucleus (VMH) of the hypothalamus (HYP) ( Smith-1990 ). It is found in the human ( Mai-1997 ), macaque ( Paxinos-2009a ), rat ( Paxinos-2009b ) and mouse ( Franklin-2008 ). It receives major inputs from the amygdala (AMG)...directly from the medial amygdalar nucleus (MEA) and indirectly from the basolateral amygdalar nucleus (BLN) through the central amygdalar nucleus (CEA) ( DeVito-1982; Amaral-1992 ). Electrical stimulation of the PFX produces the cardiovascular component of defensive responses to threatening stimuli ( Smith-1990; Smith-2007 ). It is the part of HYP most involved in sham rage ( Crosby-1962 ) and fear conditioning ( Smith 1990; Pare-2004 ). It is considered the central controller of cardiovascular responses in the instinctive behavioral control system ( Bowden-2021 ). Final 20 Mar 2025.

Also known as: area LH/PF, lateral hypothalamus-perifornical area, perifornical hypothalamus, perifornical area, LH/PF region, Nucleus perifornicalis hypothalami, interfornical nucleus, Nucleus perifornicalis, parafornical nucleus, perifornical nucleus

NeuroNames ID: 3597

All Names & Sources

1 of 16

Showing 16 synonym(s) - Use arrows to navigate

Showing 16 synonym(s)

Name:

area LH/PF

Language:

English

Organism:

Papio

Source:

Smith-1990

Citation:

Am J Physiol 1990 Nov;259(5 Pt 2):R943-54

Source Title:

Neurons controlling cardiovascular responses to emotion are located in lateral hypothalamus-perifornical region.

Name:

HACER

Language:

acronym

Organism:

Papio

Source:

Smith-1984

Citation:

Clin Exp Hypertens A 1984;6(1-2):185-204

Source Title:

Organization of central nervous system pathways influencing blood pressure responses during emotional behavior.

Name:

lateral hypothalamus-perifornical area

Language:

English

Organism:

Papio

Source:

Smith-1990

Citation:

Am J Physiol 1990 Nov;259(5 Pt 2):R943-54

Source Title:

Neurons controlling cardiovascular responses to emotion are located in lateral hypothalamus-perifornical region.

Name:

perifornical hypothalamus

Language:

English

Organism:

Papio

Source:

Smith-1990

Citation:

Am J Physiol 1990 Nov;259(5 Pt 2):R943-54

Source Title:

Neurons controlling cardiovascular responses to emotion are located in lateral hypothalamus-perifornical region.

Name:

perifornical area

Language:

English

Organism:

Papio

Source:

Smith-1984

Citation:

Clin Exp Hypertens A 1984;6(1-2):185-204

Source Title:

Organization of central nervous system pathways influencing blood pressure responses during emotional behavior.

Name:

LH/PF

Language:

acronym

Organism:

Papio

Source:

Smith-1990

Citation:

Am J Physiol 1990 Nov;259(5 Pt 2):R943-54

Source Title:

Neurons controlling cardiovascular responses to emotion are located in lateral hypothalamus-perifornical region.

Name:

LH/PF region

Language:

English

Organism:

Papio

Source:

Smith-1990

Citation:

Am J Physiol 1990 Nov;259(5 Pt 2):R943-54

Source Title:

Neurons controlling cardiovascular responses to emotion are located in lateral hypothalamus-perifornical region.

Name:

PFX

Language:

acronym

Organism:

Unspecified

Source:

NeuroNames

Citation:

University of Washington, Seattle, WA

Source Title:

NeuroNames

Name:

perifornical area

Language:

English

Organism:

Papio

Source:

Smith-1984

Citation:

Clin Exp Hypertens A 1984;6(1-2):185-204

Source Title:

Organization of central nervous system pathways influencing blood pressure responses during emotional behavior.

Name:

PeF

Language:

acronym

Organism:

mouse

Source:

Franklin-2008

Citation:

Compact Third Edition, Amsterdam: Elsevier Academic Press

Source Title:

The Mouse Brain in Stereotaxic Coordinates

Name:

PeFLH

Language:

acronym

Organism:

rat

Source:

Paxinos-2009b

Citation:

Sixth Edition, Amsterdam: Amsterdam: Elsevier-Academic Press

Source Title:

The Rat Brain in Stereotaxic Coordinates

Name:

Nucleus perifornicalis hypothalami

Language:

Latin

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

Name:

interfornical nucleus

Language:

English

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

Name:

Nucleus perifornicalis

Language:

Latin

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

Name:

parafornical nucleus

Language:

English

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

Name:

perifornical nucleus

Language:

English

Organism:

human

Source:

Mai-1997

Citation:

San Diego: Academic Press, 1997

Source Title:

Atlas of the Human Brain

No illustrations found

No illustrations available for this concept.

No specie structures found

No specie structures available for this concept.

No models found

No models available for this concept.