hippocampal complex (HPC)

The term hippocampal complex refers to the functionally defined combination of gray and white matter components that make up the seahorse-shaped structure revealed by dissection on the floor of the lateral ventricle in the human ( Shaw-1997 Glasser-2016 ) and the macaque ( Martin-2000 ). ('hippocampus' is Latin for 'seahorse'.) Part of the cerebral cortex, the hippocampal complex is an infolding of the part of hippocampus in the ventral part of the limbic lobe into the lateral ventricle. It consists of three predominantly gray matter structures: the dentate gyrus, CA fields, and subiculum, and two predominantly white matter structures: the alveus and fimbria ( Carpenter-1983 ). While some authors refer to the transitional area of the CA1 field into the subiculum as a histologically separate structure ( Carpenter-1983 Paxinos-2009a ), that area, the presubiculum, does not appear in a functional segmentation of the human cerebral cortex ( Glasser-2016 ). In primates the HPC is a relatively flat structure the rostral end of which abuts the amygdala and curves medially to form the uncus. In rodents, where it constitutes a much greater portion of the cerebral cortex it curves up caudally into a C-shaped structure. Updated 18 Jun 2024.

Also known as: hippocampus of Crosby, hippocampal complex, hippocampal formation of Carpenter, hippocampus of Glasser, Hippocampus of Stephan, hippocampal region of squire

NeuroNames ID: 177

All Names & Sources

Showing 12 synonym(s)

Language
Name
Source
English
hippocampal complex
English
hippocampal formation of Carpenter
English
hippocampal region of squire
English
hippocampus of Crosby
English
hippocampus of Glasser
Species With The Structure
Equivalent By Human Macaque Rat Mouse
Internal Structure Has The Structure Relevant Data Not Located Relevant Data Not Located Relevant Data Not Located

Showing 1 record(s)

Basis
Has Equivalent
Organism
Their Name
Source
Internal Structure
Yes
hippocampus of Crosby
Models Where It Appears
Structural CNS Model - Macaque

Brain structures of the macaque are illustrated in BrainInfo’s NeuroMaps macaque brain atlas. Structures are grouped by proximity in a hierarchy corresponding to the central nervous system hierarchy of NeuroNames ( Bowden-1995 Martin-2000 ). Structures in the NeuroMaps atlas are based on the segmentation of an MRI of the brain of a 3-year old male rhesus macaque (Macaca mulatta). The atlas is most useful for targeting structures for implantating electrodes and chemtrodes. Updated 29 Oct 2025.