hippocampal formation (HPF)

The term hippocampal formation refers to a functionally defined composite structure of the limbic lobe defined on the basis of internal structure, connectivity, and role in the recording, storage and retrieval of declarative memory. In the primates, it includes the hippocampal complex, the presubiculum, parasubiculum and entorhinal cortex of the anterior parahippocampal gyrus ( Insausti-2012 ). The rat ( Swanson-2004 ) and the mouse ( Franklin-2008 ) have an equivalent combination of structures except that it includes a postsubiculum and it is located ventrally on the mesial surface at the caudal pole of the cerebral hemisphere ( Squire-2004 ). The histological components in the rat ( Swanson-2004 ) and the mouse ( Hof-2000 ).are the same as in primates except that in those species it also includes the fasciola cinerea and and indusium griseum. In the noninvasive imaging literature, the hippocampal formation, which is located in the limbic lobe, is commonly referred to by the misnomer 'medial temporal lobe'. (updated 18 May 2024).

Also known as: hippocampal formation, hippocampus

NeuroNames ID: 2026

All Names & Sources

Showing 4 synonym(s)

Name:

hippocampal formation

Language:

English

Organism:

human

Citation:

Source Title:

Hippocampal Formation

Name:

hippocampal formation

Language:

English

Organism:

rat

Source:

Swanson-2004

Citation:

Third Edition, Elsevier Academic Press, Oxford, 2004

Source Title:

Brain Maps: Structure of the Rat Brain.

Name:

HPF

Language:

acronym

Organism:

Unspecified

Source:

NeuroNames

Citation:

University of Washington, Seattle, WA

Source Title:

NeuroNames

Name:

hippocampus

Language:

English

Organism:

Unspecified

Citation:

Source Title:

Hippocampus as comparator: role of the two input and two output Systems of the hippocampus in selection and registration of information

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Models Where It Appears
Functional CNS Model - Rat

The Functional CNS Model - Rat (FMrat) ( Swanson-2004) is one of three hierarchical models representing the internal organization of the central nervous system (CNS). The others are the Structural CNS Model - Human (SThmn) and the Functional CNS Model - Human (FMhmn). The FMrat model represents the basic organization of the mouse ( Hof-2000 AMBA-2024 ) and, presumably, other rodents. Functional CNS models differ from structural models in that structures are defined and named by connectivity rather than by proximity to other structures at the same level. Functional models are more useful for representing longitudinal components of are grouped based on information drawn from multiple neuroscientific disciplines. such as connections, neurochemical characteristics, and role in physiogical and behavioral processes. While the Functional Model was developed primarily for an atlas of the rat brain ( Swanson-2004 ), the hierarchical organization of structures is for the most part applicable to the human, macaque, mouse and other mammalian brains as well. Structures at lower levels of the Functional CNS hierarchy are largely the same as in the Classical and Developmental Models, i.e., they were originally identified by stains for gray matter (Nissl substance) and white matter (myelin). At the next higher level they are grouped into basic connectional and functional systems of the CNS, such as the subcortical sensory systems, the brainstem motor system and the behavioral state system. At the highest levels CNS structures are grouped on the basis of dissection and embryologic precursors into cerebrum ( cerebral cortex and cerebral nuclei ), cerebellum, and cerebrospinal trunk.